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Health Science Roundup Week of Sept 15, 2021

The latest science in life extension and age reversal — in humans and dogs.

Altos Labs. Jeff Bezos is joining Russian-born billionaire Yuri Milner in creating a competitor to the Google-backed Calico. Altos is pursuing biological reprogramming technology, a way to rejuvenate cells in the lab that some scientists think could be extended to revitalize entire animal bodies, ultimately prolonging human life. They are bringing some A-list scientists including Steve Horvath, whom we know as the creator of the epigenetic age measuring Horvath Clock.

Peter Attia with Matt Kaeberlein, PhD: The biology of aging, rapamycin, and other interventions that target the aging process. Fascinating if nerdy dive into why there are no good data-based definitions of aging, rapamycin, fasting, and mTOR. He discusses the current state of the literature of testing rapamycin (and rapalogs) in animals and humans, including Matt’s Dog Aging Project, and provides insights into how we can improve future trials by conceptualizing risk, choosing better endpoints, and working with regulators to approve such trials.

Dog Longevity Vet: Our canine friends don’t live as long as we do, but many of the currently experimental interventions for people are being used safely on dogs now.  If anyone has lost a dog, you know how heart wrenching that can feel. We have not used them, but a friend of AGEIST has and reports they do good work.

Rejuvenate Bio: a Harvard startup, secured over $10M in April to tackle age-related conditions with a single injection — and it’s experimenting on age reversal with dogs. Anti-aging gene therapy involves altering an organism’s DNA to reverse aging. If proven in our canine friends, the next step will be human trials.

Sauna for proven healthspan extension.  In recent decades, sauna bathing has emerged as a means to increase lifespan and improve overall health, based on compelling data from observational, interventional, and mechanistic studies. Dr Rhonda Patrick’s extensive and exhaustive investigation into the positive health effects of getting hot.

 

See medical disclaimer below. ↓

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The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.

David Stewart
David is the founder and face of AGEIST. He is an expert on, and a passionate champion of the emerging global over-50 lifestyle. A dynamic speaker, he is available for panels, keynotes and informational talks at david@agei.st.

 

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