We are fascinated with the findings that one commonality that centenarians have is diverse microbiota. How can one increase diversity in their gut microbiome? Researchers at Tianjin Medical University have found in animal trials that supplementing with the senolytic quercetin had beneficial effects on gut bacteria, increasing counts of the beneficial genera Clostridia, Bifidobacterium, and Lactobacillus, and reducing counts of Fusobacterium and Enterococcus, which are associated with negative health outcomes. To date, there is not yet evidence that this study can be extrapolated to humans; however, this is a step in the right direction to understand whether quercetin supplementation will have the same effect.
Study cited: NCBI